A noninvasive imaging technique to evaluate therapeutic efficacy after injection of n-butyl-2- cyanoacrylate tissue adhesive into gastric varices: a case report.

A novel use of multidetector computed tomographic intravenous (MDCT IV) portography in the evaluation of gastric varices treated with tissue adhesive is described. A 55-year-old man presented with upper gastrointestinal hemorrhage as a result of bleeding gastric varices. The patient was stabilized and the gastric varices were treated with n-butyl-2-cyanoacrylate (two injections, total 7.5 mL). MDCT IV portography performed after injection revealed thrombosis of all but one of the submucosally based gastric varices. The endoscopist who performed repeat endoscopy three weeks later was then able to direct therapy at the remaining patent submucosally based gastric varix. This represents the first reported use of MDCT IV portography in the evaluation of treatment adequacy in a patient with gastric varices treated with n-butyl-2-cyanoacrylate.
AuthorsB J Spier, A J Taylor, P R Pfau, A Said, D V Gopal
JournalCanadian journal of gastroenterology = Journal canadien de gastroenterologie (Can J Gastroenterol) Vol. 23 Issue 6 Pg. 412-4 (Jun 2009) ISSN: 0835-7900 [Print] Canada
PMID19543570 (Publication Type: Case Reports, Journal Article)
Chemical References
  • Tissue Adhesives
  • Enbucrilate
  • Enbucrilate (administration & dosage)
  • Endoscopy
  • Esophageal and Gastric Varices (pathology, radiography, therapy)
  • Humans
  • Male
  • Middle Aged
  • Outcome Assessment (Health Care)
  • Portography
  • Sclerotherapy
  • Tissue Adhesives (administration & dosage)
  • Tomography, X-Ray Computed

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.
Realize the full power of the drug-disease research network!

Choose Username:
Verify Password: