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Endoscopic topical application of Ankaferd Blood Stopper for neoplastic gastrointestinal bleeding: A retrospective analysis.

AbstractAIM:
The aim of this study was to retrospectively assess the haemostatic efficacy of the endoscopic topical use of Ankaferd Blood Stopper (ABS) in the setting of neoplastic GI bleeding.
METHODS:
The records of 10 patients with neoplastic GI bleeding (7 gastric, 3 rectal) were evaluated retrospectively. Written informed consent regarding the off-label use of ABS as a means of attaining haemostasis had been obtained from all of the patients prior to the procedure. In all patients, ABS was applied topically. Rates of bleeding control and post-procedural complications were documented.
RESULTS:
Haemostasis was achieved in all patients within seconds of endoscopic application of ABS, with no immediate complications. Seven patients underwent subsequent cancer surgery after a bleeding-free post-procedural period.
CONCLUSIONS:
ABS as a novel haemostatic agent could have a potential benefit in controlling bleeding from GI tumours. Prospective controlled studies are needed to help establish its efficacy, and perhaps offer a comparison to conventional haemostatic interventions.
AuthorsMevlut Kurt, Meral Akdogan, Ibrahim Koral Onal, Murat Kekilli, Mehmet Arhan, Ali Shorbagi, Salih Aksu, Ozlem Kar Kurt, Ibrahim Celalettin Haznedaroglu
JournalDigestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver (Dig Liver Dis) Vol. 42 Issue 3 Pg. 196-9 (Mar 2010) ISSN: 1878-3562 [Electronic] Netherlands
PMID19540818 (Publication Type: Journal Article)
Copyright2009 Editrice Gastroenterologica Italiana S.r.l. Published by Elsevier Ltd. All rights reserved.
Chemical References
  • Hemostatics
  • Plant Extracts
  • ankaferd blood stopper
Topics
  • Administration, Topical
  • Aged
  • Aged, 80 and over
  • Endoscopy, Gastrointestinal
  • Female
  • Gastrointestinal Hemorrhage (drug therapy, etiology)
  • Hemostatics (administration & dosage)
  • Humans
  • Male
  • Middle Aged
  • Off-Label Use
  • Plant Extracts (administration & dosage)
  • Rectal Neoplasms (complications)
  • Retrospective Studies
  • Stomach Neoplasms (complications)

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