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[Danazol - effective second line therapy in idiopathic thrombocytopenic purpura in children. Three case reports].

Abstract
Danazol is an accredited second line drug for idiopathic thrombocytopenic purpura (ITP) in adults. There are very few positions in the literature about using danazol in children, although some articles quote its evident efficacy. In this paper we present three cases of children treated with danazol. The routine treatment in these ITP cases was ineffective. The result was stabilization of platelet count and avoidance of splenectomy.
AuthorsAnna Szmydki-Baran, Anna Adamowicz-Salach, Sydonia Gołebiowska-Staroszczyk
JournalMedycyna wieku rozwojowego (Med Wieku Rozwoj) 2008 Oct-Dec Vol. 12 Issue 4 Pt 2 Pg. 1130-4 Poland
Vernacular TitleDanazol-skutecny lek drugiego rzutu w idiopatycznej plamicy małopłytkowej u dzieci. Opis 3 przypadkow.
PMID19531838 (Publication Type: Case Reports, English Abstract, Journal Article)
Chemical References
  • Danazol
Topics
  • Child
  • Danazol (therapeutic use)
  • Female
  • Humans
  • Platelet Count
  • Purpura, Thrombocytopenic, Idiopathic (blood, drug therapy, surgery)
  • Splenectomy
  • Treatment Failure

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