Abstract | AIM: To study the microbiological characteristics of patients with severe bacterial keratitis in Bordeaux, France, as well as the species' resistance to fluoroquinolones. METHODS: We conducted a retrospective study of 57 patients presenting severe bacterial keratitis over 20 months. The positive bacteriological cultures of the corneal smears, bacteria, and the antibiogram were listed. RESULTS: Fifty-seven patients with severe bacterial keratitis were hospitalized from March 2005 to November 2006. Pseudomonas aeruginosa (n=17), Staphylococcus aureus (n=16), and coagulase-negative Staphylococcus (n=10) were the most frequent species. P. aeruginosa was sensitive in 100% of cases to ciprofloxacin, S. aureus was sensitive in 94% of cases to ciprofloxacin, and coagulase-negative Staphylococcus species were sensitive in 100% of cases to ciprofloxacin. No significant different was noted between ciprofloxacin, levofloxacin, and moxifloxacin on the bacteria studied (p>0.05). CONCLUSION: In this study, except for the Streptococcus species, ciprofloxacin was effective against the species responsible for severe bacterial keratitis.
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Authors | N Mesplié, J Kérautret, S Léoni, V Dubois, J Colin |
Journal | Journal francais d'ophtalmologie
(J Fr Ophtalmol)
Vol. 32
Issue 4
Pg. 273-6
(Apr 2009)
ISSN: 1773-0597 [Electronic] France |
Vernacular Title | Kératites bactériennes sévères et sensibilité des germes aux fluoroquinolones. |
PMID | 19515343
(Publication Type: English Abstract, Journal Article)
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Chemical References |
- Anti-Bacterial Agents
- Fluoroquinolones
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Topics |
- Adolescent
- Adult
- Aged
- Aged, 80 and over
- Anti-Bacterial Agents
(pharmacology)
- Bacteria
(drug effects)
- Child
- Child, Preschool
- Fluoroquinolones
(pharmacology)
- Humans
- Infant
- Keratitis
(microbiology)
- Microbial Sensitivity Tests
- Middle Aged
- Retrospective Studies
- Severity of Illness Index
- Young Adult
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