Chronic tongue ulceration resolved by sulpiride: a report of two cases.

Abstract

We report two patients with chronic tongue ulceration who were successfully treated using sulpiride. The clinical diagnosis was oral candidiasis related to long-term steroid treatment. The results of the culture test and cytological examination supported this diagnosis, but antifungal treatment was ineffective and the tongue pain in these patients became more severe. Furthermore, the pain could not be relieved by nonsteroidal anti-inflammatory drugs (NSAIDs). We therefore prescribed sulpiride in addition to NSAIDs to reduce the tongue pain. A consequent improvement in both pain severity and ulceration was observed 2-3 weeks after sulpiride administration.

• Authors: H Terai, M Shimahara
• Journal: Clinical and experimental dermatology (Clin Exp Dermatol) Vol. 34 Issue 5 Pg. e40-2 (Jul 2009) ISSN: 1365-2230 [Electronic] England
• PMID: 19508474 (Publication Type: Case Reports, Journal Article)

Chemical References

• Dopamine Antagonists
• Sulpiride

Topics

• Aged, 80 and over
• Candidiasis, Oral (drug therapy, pathology)
• Chronic Disease
• Dopamine Antagonists (therapeutic use)
• Female
• Humans
• Oral Ulcer (drug therapy, pathology)
• Sulpiride (therapeutic use)
• Tongue Diseases (drug therapy, pathology)