Treatment of acrodermatitis continua with topical 8-methoxypsoralen plus local narrowband ultraviolet B phototherapy.

Abstract

Treatment of acrodermatitis continua of Hallopeau (ACH) is known to be difficult. A 24-year-old man presented with an 11-year history of recurrent flares of painful pustular and scaly lesions on the distal portion of his fingers and toes, with persistent nail dystrophy. Based on the clinical and histopathological findings, ACH was diagnosed. The patient was treated with topical 8-methoxypsoralen (8-MOP) without occlusion, plus local narrowband ultraviolet B (NB-UVB) phototherapy. The patient did not use any other medication between sessions except topical emollients. Ten weeks later, when the patient had received 20 sessions, almost all the lesions had cleared. We report the first case of ACH which successfully responded to treatment with 8-MOP/NB-UVB.

• Authors: Selda Pelin Kartal Durmazlar, Hatice AKPINAR, Cemile EREN, Fatma ESKIOGLU, Semih TATLICAN
• Journal: European journal of dermatology : EJD (Eur J Dermatol) 2009 Sep-Oct Vol. 19 Issue 5 Pg. 478-80 ISSN: 1167-1122 [Print] France
• PMID: 19502154 (Publication Type: Case Reports, Journal Article)

Chemical References

• Methoxsalen

Topics

• Acrodermatitis (drug therapy, pathology)
• Administration, Topical
• Adult
• Humans
• Male
• Methoxsalen (administration & dosage)
• Ultraviolet Therapy