[Effect of small-doses ketamine on postoperative pain management with combinations morphine/ketoprofen or lidol/ketoprofen after major gynecological surgery] [corrected].

Abstract	We examine the potential beneficial effect of small-doses ketamine on postoperative pain management with combinations morphine/ketoprofen or lidol/ketoprofen after major gynecological surgery. After patient written consent, 50 healthy women, which were scheduled for abdominal gynecological surgery were randomly allocated into two groups depending of postoperative analgesic technique--morphine/ ketoprofen or lidol/ketoprofen. The quality of postoperative analgesia, total opioid consumption for the first postoperative day and unwished side effects were assessed. Demographic and surgical data were identical in the groups. Using ketamine during the anesthesia improve quality of postoperative analgesia in accordance with less opioid consumption for the combination morphine/ ketoprofen, but not for the combination lidol/ketoprofen. Adding small doses ketamine to combination morphine/ketoprofen improve postoperative analgesia; reduce morphine consumption and incidences of morphine-related side effects after major gynecological surgery.
Authors	B Tablov, V Tablov, I Popov
Journal	Akusherstvo i ginekologiia (Akush Ginekol (Sofiia)) Vol. 48 Issue 1 Pg. 25-8 ( 2009) ISSN: 0324-0959 [Print] Bulgaria
PMID	19496460 (Publication Type: English Abstract, Journal Article)
Chemical References	Analgesics, Opioid Anesthetics, Dissociative Anti-Inflammatory Agents, Non-Steroidal Ketamine Morphine Ketoprofen Meperidine
Topics	Abdomen (surgery) Adolescent Adult Aged Analgesics, Opioid (adverse effects, therapeutic use) Anesthetics, Dissociative (administration & dosage, therapeutic use) Anti-Inflammatory Agents, Non-Steroidal (therapeutic use) Drug Therapy, Combination Female Gynecologic Surgical Procedures Humans Ketamine (administration & dosage, therapeutic use) Ketoprofen (therapeutic use) Meperidine (therapeutic use) Middle Aged Morphine (adverse effects, therapeutic use) Young Adult

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