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Estulic monotherapy and combined antihypertensive therapy.

Abstract
The antihypertensive effect of Estulic has been examined over a 12-month period in 101 hypertensive patients. Estulic tablet proved to be effective in form of monotherapy especially in the treatment of mild hypertension, in form of combination therapy in hypertension of medium severity. Using Estulic the number and doses, of the formerly administrated drugs could be reduced. The blood pressure of the patients was stabilized on a significantly lower level, changes in the laboratory parameters were not observed. In 60% of the patients improvement of the subjective complaints was observed. On the basis of the examinations guanfacin proved to be an effective drug in the treatment of hypertension of different severity degrees due to its favourable antihypertensive action, few side-effects, and the possibility of drug administration in daily single doses.
AuthorsA Faluhelyi, A Szentkereszty
JournalTherapia Hungarica (English edition) (Ther Hung) Vol. 39 Issue 2 Pg. 87-9 ( 1991) ISSN: 0133-3909 [Print] Hungary
PMID1948783 (Publication Type: Clinical Trial, Journal Article)
Chemical References
  • Guanfacine
Topics
  • Aged
  • Blood Pressure (drug effects)
  • Drug Therapy, Combination
  • Female
  • Guanfacine (administration & dosage, pharmacology, therapeutic use)
  • Humans
  • Hypertension (drug therapy)
  • Male

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