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Subtypes of clients with serious mental illness and co-occurring disorders: latent-class trajectory analysis.

AbstractOBJECTIVE: This study identified and characterized groups of clients who have serious mental illness and co-occurring substance use disorders. METHODS: Substance abuse recovery of 177 clients with co-occurring disorders was followed for ten years with multiperspective ratings every six months. Latent-class trajectory analysis was used to identify subgroups; profile analysis was used to examine baseline risk factors and treatment participation. RESULTS: Two ratings of substance abuse recovery-stage of treatment and abstinence-were highly concordant and identified the same four groups: early recovery, unstable recovery, late recovery, and no recovery. The early-recovery group was characterized by less severe substance use disorders at baseline and by use of clozapine. The unstable-recovery group was too small for statistical analyses. The late-recovery group was similar to the no-recovery group at baseline but participated more extensively in treatments, especially residential dual-diagnosis programs, during the first three years of follow-up. CONCLUSIONS: Latent-class trajectory analysis based on ten-year trajectories of substance abuse recovery identified clinically meaningful groups among clients with serious mental illness and co-occurring substance use disorders. Profiles of the three most common groups suggest differential clinical approaches for each.
AuthorsHaiyi Xie, Gregory J McHugo, Robert E Drake (Affiliation: Dartmouth Psychiatric Research Center, 2 Whipple Pl., Suite 202, Lebanon, NH 03766, USA. haiyi.xie at dartmouth.edu)
JournalPsychiatric services (Washington, D.C.) (Psychiatr Serv) Vol. 60 Issue 6 Pg. 804-11 (Jun 2009) ISSN: 1557-9700 [Electronic] United States
PMID19487351 (Publication Type: Journal Article, Research Support, N.I.H., Extramural)
Topics
  • Adult
  • Diagnosis, Dual (Psychiatry)
  • Female
  • Humans
  • Interviews as Topic
  • Longitudinal Studies
  • Male
  • Mental Disorders
  • Patients (classification)
  • Prospective Studies
  • Severity of Illness Index
  • Substance-Related Disorders (rehabilitation)