Abstract |
A 20-day-old female infant developed fever. Sepsis evaluation revealed cerebrospinal fluid (CSF) pleocytosis and a modestly decreased CSF glucose. After 48 hours of broad-spectrum antibiotics, the infant remained febrile. Repeat CSF analysis showed increased pleocytosis and a very low glucose value. Subsequently, a rectothecal fistula and sacral abnormalities were found, leading to the diagnosis of Currarino syndrome. Parameningeal foci should be considered in treatment-resistant meningitis.
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Authors | Autumn S Kiefer, Priyanka Gupta, Salman Kirmani, Kara Schwartz, Nancy Henry, Philip R Fischer |
Journal | The Pediatric infectious disease journal
(Pediatr Infect Dis J)
Vol. 28
Issue 6
Pg. 547-9
(Jun 2009)
ISSN: 0891-3668 [Print] United States |
PMID | 19483525
(Publication Type: Case Reports, Journal Article)
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Chemical References |
- Anti-Bacterial Agents
- Antiviral Agents
- Homeodomain Proteins
- MNX1 protein, human
- Transcription Factors
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Topics |
- Abnormalities, Multiple
(diagnosis)
- Anal Canal
(abnormalities)
- Anti-Bacterial Agents
(therapeutic use)
- Antiviral Agents
(therapeutic use)
- Constriction, Pathologic
- Female
- Homeodomain Proteins
(genetics)
- Humans
- Infant, Newborn
- Meningitis
(cerebrospinal fluid, diagnosis, drug therapy)
- Meningocele
- Rectal Fistula
- Sacrum
(abnormalities)
- Syndrome
- Transcription Factors
(genetics)
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