[Hypokalemia from ectopic ACTH secretion and hypothiroidism in patient affected by small cell lung cancer].

Abstract

Endocrin paraneoplastic syndromes are characterized by an ectopic hormonal production. The ectopic adrenocorticotropic hormone (ACTH) secretion is often associated with small cell lung cancer. We report the case of 64-years-old man with persistent hypokalemia in Cushing's syndrome due to ectopic ACTH secretion. The patient was affected by small cell lung cancer and presented an hypothiroidism too. A proper chemotherapy resulted in remission of the hypokalemia, but the hypothiroidism was not influenced during our observation period.

• Authors: Massimo Bindi, Daniela Moruzzo, Massimiliano Pinelli, Javier Rosada, Maido Castiglioni
• Journal: Recenti progressi in medicina (Recenti Prog Med) Vol. 100 Issue 3 Pg. 137-9 (Mar 2009) ISSN: 0034-1193 [Print] Italy
• Vernacular Title: Ipokaliemia da produzione ectopica di ACTH ed ipotiroidismo in paziente affetto da microcitoma.
• PMID: 19475841 (Publication Type: Case Reports, Journal Article)

Topics

• ACTH Syndrome, Ectopic (complications, diagnosis)
• Biopsy
• Carcinoma, Small Cell (diagnostic imaging, metabolism, pathology)
• Cushing Syndrome (diagnosis, etiology)
• Diagnosis, Differential
• Humans
• Hypokalemia (etiology)
• Hypothyroidism (etiology)
• Lung (pathology)
• Lung Neoplasms (diagnostic imaging, metabolism, pathology)
• Male
• Middle Aged
• Radiography, Thoracic
• Tomography, X-Ray Computed