Abstract | AIM:
Bicyclol is a synthetic anti- hepatitis drug with anti-oxidative property. The purpose of this study was to investigate the effect of bicyclol on hepatic ischemia/reperfusion (I/R) injury and related mechanisms. METHODS: RESULTS: CONCLUSION:
Bicyclol had a remarkable protective effect on hepatic I/R injury, which was partially due to inhibiting the expression of TLR4 and NF-kappaB via its ability to attenuate oxidative stress and endotoxin.
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Authors | Xiao-Min Yao, Hui Chen, Yan Li |
Journal | Hepatology research : the official journal of the Japan Society of Hepatology
(Hepatol Res)
Vol. 39
Issue 8
Pg. 833-42
(Aug 2009)
ISSN: 1386-6346 [Print] Netherlands |
PMID | 19473433
(Publication Type: Journal Article)
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