HOMEPRODUCTSCOMPANYCONTACTFAQResearchDictionaryPharmaSign Up FREE or Login

Orbital wall fracture repair using Seprafilm.

AbstractPURPOSE:
Seprafilm is a hybrid product of carboxymethylcellulose and sodium hyaluronate that can act as an absorbable barrier to decrease the formation and severity of postoperative adhesions in abdominal, thoracic, and pelvic surgeries. The authors report their experience with use of Seprafilm in "trap door" orbital wall fracture repair.
METHODS:
Retrospective case series of 4 consecutive patients with trap door orbital wall fractures secondary to blunt trauma with entrapped orbital soft tissue who underwent surgical repair with placement of Seprafilm implant in 2008. Orbitotomy was performed via standard transconjunctival and/or transcaruncular approaches with release of entrapped tissues, and placement of Seprafilm implant over the fracture site without fixation. Patients were followed for at least 6 months. Ophthalmic and orbital examinations, including ocular motility and Hertel exophthalmometry measurements, were recorded.
RESULTS:
All 6 orbital wall fractures (4 floor, 2 medial wall) were successfully corrected with resolution of restrictive motility in the follow-up period (average 10 months; range 6 months to 1.5 years). Mean patient age was 13.5 years (range, 9-20 years). Two of the 4 patients had 2 separate fractures. There were no complications and no need for reoperation.
CONCLUSIONS:
Seprafilm may have a role in reconstruction of the "trap door" type of orbital wall fractures. The ease of use, lack of fixation, and absorbable properties without inflammation are encouraging for further study.
AuthorsMehryar Taban, Tanuj Nakra, Ronald Mancini, Raymond S Douglas, Robert A Goldberg
JournalOphthalmic plastic and reconstructive surgery (Ophthalmic Plast Reconstr Surg) 2009 May-Jun Vol. 25 Issue 3 Pg. 211-4 ISSN: 1537-2677 [Electronic] United States
PMID19454933 (Publication Type: Journal Article)
Chemical References
  • Membranes, Artificial
  • Seprafilm
  • Hyaluronic Acid
Topics
  • Adolescent
  • Child
  • Follow-Up Studies
  • Humans
  • Hyaluronic Acid
  • Male
  • Membranes, Artificial
  • Orbital Fractures (diagnostic imaging, etiology, surgery)
  • Prostheses and Implants
  • Plastic Surgery Procedures (adverse effects, methods)
  • Retrospective Studies
  • Tissue Adhesions (prevention & control)
  • Tomography, X-Ray Computed
  • Treatment Outcome
  • Wounds, Nonpenetrating (complications)
  • Young Adult

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.
Realize the full power of the drug-disease research graph!


Choose Username:
Email:
Password:
Verify Password:
Enter Code Shown: