| Abstract | We describe a unique case of a recurrence of Wegener's granulomatosis (WG) that presented with oral pain involving a left maxillary molar, which thereafter led to an extraction. Oral lesions with a classical appearance of strawberry gingivitis developed following the extraction. The primary disease did not have any oral manifestations. Both the primary disease and recurrence responded to rituximab, a monoclonal B-cell depleting antibody. Rituximab is emerging as a drug with significant potential to improve treatment of primary and, as described in this case, recurrent WG. |
| Authors | Konrad S Staines, Bernard Higgins
(Affiliation: Newcastle Dental Hospital & School, Newcastle upon Tyne, UK. konrad.staines at nuth.nhs.uk)
|
| Journal | Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics
(Oral Surg Oral Med Oral Pathol Oral Radiol Endod)
Vol. 108
Issue 1
Pg. 76-80
(Jul 2009)
ISSN: 1528-395X [Electronic] United States |
| PMID | 19451001
(Publication Type: Case Reports, Journal Article)
|
| Chemical References |
- Anti-Inflammatory Agents
- Antibodies, Monoclonal
- Antigens, CD20
- Glucocorticoids
- Immunologic Factors
- rituximab
- Prednisolone
|
| Topics |
- Adult
- Anti-Inflammatory Agents
(therapeutic use)
- Antibodies, Monoclonal
(therapeutic use)
- Antigens, CD20
(therapeutic use)
- Female
- Follow-Up Studies
- Gingivitis
(diagnosis, drug therapy)
- Glucocorticoids
(therapeutic use)
- Humans
- Immunologic Factors
(therapeutic use)
- Prednisolone
(therapeutic use)
- Recurrence
- Tooth Extraction
- Toothache
(therapy)
- Wegener Granulomatosis
(diagnosis, drug therapy)
|
