Abstract |
The hemostatic efficacy of ethamsylate studied by a matched-pair analysis was not proved to be statistically significant. The appearance of bleeding signs as well as the frequency of platelet transfusions have been examined. An important side-effect was found in patients receiving ethamsylate: severe leucocytopenia (less than 1000 leucocytes/microliters) was noticed more frequently followed by an enhanced susceptibility to infections. The incidence of septic infections was proved to be significantly increased in an extended sample of 100 patients.
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Authors | L Ritter, H Schlösser, J Boos, P Heyen |
Journal | Klinische Padiatrie
(Klin Padiatr)
1991 Jul-Aug
Vol. 203
Issue 4
Pg. 296-301
ISSN: 0300-8630 [Print] Germany |
Vernacular Title | Einfluss von Etamsylat auf die Blutungsneigung von Kindern mit onkologischen Erkrankungen. Retrospektive Matched-pair-Analyse von 64 Patienten bei Untersuchung von 100 Patienten der Universitätskinderklinik Münster. |
PMID | 1942936
(Publication Type: Clinical Trial, English Abstract, Journal Article, Multicenter Study)
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Chemical References |
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Topics |
- Blood Coagulation Tests
- Bone Neoplasms
(blood, drug therapy)
- Child
- Child, Preschool
- Ethamsylate
(administration & dosage, adverse effects)
- Hemorrhagic Disorders
(blood, drug therapy)
- Humans
- Leukemia, Myeloid, Acute
(blood, drug therapy)
- Matched-Pair Analysis
- Osteosarcoma
(blood, drug therapy)
- Platelet Count
(drug effects)
- Precursor Cell Lymphoblastic Leukemia-Lymphoma
(blood, drug therapy)
- Retrospective Studies
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