HOMEPRODUCTSCOMPANYCONTACTFAQResearchDictionaryPharmaSign Up FREE or Login

[Effect of etamsylate on hemorrhagic diathesis of children with oncologic diseases. Retrospective matched-pair analysis of 64 patients in a study of 100 patients of the Münster University Pediatric Clinic].

Abstract
The hemostatic efficacy of ethamsylate studied by a matched-pair analysis was not proved to be statistically significant. The appearance of bleeding signs as well as the frequency of platelet transfusions have been examined. An important side-effect was found in patients receiving ethamsylate: severe leucocytopenia (less than 1000 leucocytes/microliters) was noticed more frequently followed by an enhanced susceptibility to infections. The incidence of septic infections was proved to be significantly increased in an extended sample of 100 patients.
AuthorsL Ritter, H Schlösser, J Boos, P Heyen
JournalKlinische Padiatrie (Klin Padiatr) 1991 Jul-Aug Vol. 203 Issue 4 Pg. 296-301 ISSN: 0300-8630 [Print] Germany
Vernacular TitleEinfluss von Etamsylat auf die Blutungsneigung von Kindern mit onkologischen Erkrankungen. Retrospektive Matched-pair-Analyse von 64 Patienten bei Untersuchung von 100 Patienten der Universitätskinderklinik Münster.
PMID1942936 (Publication Type: Clinical Trial, English Abstract, Journal Article, Multicenter Study)
Chemical References
  • Ethamsylate
Topics
  • Blood Coagulation Tests
  • Bone Neoplasms (blood, drug therapy)
  • Child
  • Child, Preschool
  • Ethamsylate (administration & dosage, adverse effects)
  • Hemorrhagic Disorders (blood, drug therapy)
  • Humans
  • Leukemia, Myeloid, Acute (blood, drug therapy)
  • Matched-Pair Analysis
  • Osteosarcoma (blood, drug therapy)
  • Platelet Count (drug effects)
  • Precursor Cell Lymphoblastic Leukemia-Lymphoma (blood, drug therapy)
  • Retrospective Studies

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.
Realize the full power of the drug-disease research graph!


Choose Username:
Email:
Password:
Verify Password:
Enter Code Shown: