Pituitary adenoma with craniopharyngioma component.

Abstract

Neoplasms consisting of pituitary adenoma and craniopharyngioma components are rare and are being increasingly recognized. Their histogenesis is not clear. Most represent collision tumors; others are difficult to assess. Here, we describe a pituitary adenoma with an intermingled craniopharyngioma component, without forming 2 distinct mass lesions or histologic delineation. Areas that suggest a transition between the 2 components were also present. It was clinically a nonfunctioning adenoma, which was also negative for pituitary hormones by immunohistochemistry. Its histogenesis and implications are discussed with a review of the literature.

• Authors: Murat Gokden, Robert E Mrak
• Journal: Human pathology (Hum Pathol) Vol. 40 Issue 8 Pg. 1189-93 (Aug 2009) ISSN: 1532-8392 [Electronic] United States
• PMID: 19427020 (Publication Type: Case Reports, Journal Article)

Chemical References

• Biomarkers, Tumor
• beta Catenin

Topics

• Adenoma (chemistry, pathology, surgery)
• Biomarkers, Tumor (analysis)
• Craniopharyngioma (chemistry, pathology, surgery)
• Humans
• Male
• Middle Aged
• Neoplasms, Multiple Primary
• Pituitary Neoplasms (chemistry, pathology, surgery)
• Treatment Outcome
• beta Catenin (analysis)