[Relationship of nonsyndromic cleft lip and/or palate and poliovirus receptor-related 1 exon 3 polymorphisms in Han people of Jiangzhe area].

Abstract

OBJECTIVE:

To study the relationship of nonsyndromic cleft lip and/or palate (NSCL/P) and poliovirus receptor-related 1 exon3 (PVRL1exon3) polymorphisms in Han People of Jiangzhe area.

METHODS:

PVRL1exon3 was examined by polymerase chain reaction-single strand conformation polymorphism (PCR-SSCP) technique in the 50 patients with NSCL/P and 85 healthy parents.

RESULTS:

No W185X mutation was found in the PVRL1exon 3.

CONCLUSION:

It indicates that there is no relationship between NSCL/P and PVRL1exon3 in Han People in Jiangzhe area.

• Authors: Xiong Zhao, Run-song Jiang, Rui Liu, Wen-song Ye, Ning Wang, Shi-qiang Shang, Ye-feng Dai, Xu-fei Zhao
• Journal: Zhonghua zheng xing wai ke za zhi = Zhonghua zhengxing waike zazhi = Chinese journal of plastic surgery (Zhonghua Zheng Xing Wai Ke Za Zhi) Vol. 25 Issue 1 Pg. 31-3 (Jan 2009) ISSN: 1009-4598 [Print] China
• PMID: 19408722 (Publication Type: Journal Article)

Chemical References

• Cell Adhesion Molecules
• NECTIN1 protein, human
• Nectins
• Receptors, Virus

Topics

• Asian People (genetics)
• Cell Adhesion Molecules (genetics)
• Child, Preschool
• Cleft Lip (genetics)
• Cleft Palate (genetics)
• Exons
• Female
• Gene Frequency
• Genotype
• Humans
• Infant
• Male
• Nectins
• Pedigree
• Polymorphism, Genetic
• Receptors, Virus (genetics)