Low-vision rehabilitation by means of MP-1 biofeedback examination in patients with different macular diseases: a pilot study.

Abstract

Macular disease is one of the main causes of visual impairment. We studied the efficacy of low-vision rehabilitation by means of MP-1 biofeedback examination in patients with different macular disease. Five patients were enrolled (3 female and 2 male, mean age 53.8 years) and a total of 9 eyes was examined: 2 eyes with vitelliform dystrophy, 1 with a post-traumatic macular scar, 2 with Stargardt disease, 2 with myopic macular degeneration, 2 with cone dystrophy. All the patients underwent the following tests: visual acuity, reading speed, fixation test, MP-1 microperimetry. Low-vision rehabilitation, which lasted 10 weeks, consisted of 10 training sessions of 10 min for each eye, performed once a week using the MP-1 biofeedback examination. Statistical analysis was performed using Student's t-test. p values less than 0.05 were considered statistically significant. After training all patients displayed an improvement in visual acuity, fixation behaviour, retinal sensitivity and reading speed. Fixation behaviour within the 2 degrees diameter circle improved and was statistically significant for reading speed (p = 0.01). Reading speed improved from a mean value of 64.3 to 92 words/min. Our results show that audio feedback can, by increasing attentional modulation, help the brain to fix the final preferred retinal locus. Audio feedback facilitates stimuli transmission between intraretinal neurons as well as between the retina and brain, which is where the highest level of stimuli processing occurs, thereby probably supporting a "remapping phenomenon".

• Authors: Enzo M Vingolo, Serena Salvatore, Sonia Cavarretta
• Journal: Applied psychophysiology and biofeedback (Appl Psychophysiol Biofeedback) Vol. 34 Issue 2 Pg. 127-33 (Jun 2009) ISSN: 1573-3270 [Electronic] Germany
• PMID: 19396541 (Publication Type: Journal Article, Randomized Controlled Trial)

Topics

• Adult
• Aged
• Angiography
• Biofeedback, Psychology (instrumentation)
• Female
• Fixation, Ocular (physiology)
• Humans
• Macular Degeneration (pathology, rehabilitation)
• Male
• Middle Aged
• Oculomotor Muscles (physiology)
• Pilot Projects
• Reading
• Retina (physiopathology)
• Retinal Vessels (physiology)
• Scotoma (pathology)
• Surveys and Questionnaires
• Tomography, Optical Coherence
• Vision Disorders (pathology, rehabilitation)
• Visual Acuity (physiology)