Abstract | OBJECTIVE: METHOD: Eighty-seven cases of COPD patients in acute aggravated stage were chosen and divided into two groups at random. Forty-four cases in treatment group were given intravenous drip of Tanreqing (20 mL) with 5% G/NS (500 mL) once a day. Forty-three cases in control group were given intravenous drip Yanhuning injection (0.4 g) with 5% G/NS (500 mL) once a day. The courses of the treatment were both two weeks and the changes of TL-10, TNF-alpha and MPO were observed separately before and after the treatment. RESULT: The total effective rate in the treatment group was 94.31% while the control group 83.75%, which had significant difference (P<0.05). IL-10 level in both groups was comparatively lower than the healthy (P<0.01), while TNF-alpha and MPO was higher than the healthy (P<0.01). After the treatment, the TNF-alpha and MPO level in the treatment group decreased more greatly than those in the control groups (P<0.01) but the IL-10 increased a lot more than those in the control group and there existed remarkable difference (P<0.01). CONCLUSION:
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Authors | Guoliang Gong, Xin Li |
Journal | Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica
(Zhongguo Zhong Yao Za Zhi)
Vol. 34
Issue 1
Pg. 104-6
(Jan 2009)
ISSN: 1001-5302 [Print] China |
PMID | 19382463
(Publication Type: English Abstract, Journal Article, Randomized Controlled Trial)
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Chemical References |
- Cytokines
- Drugs, Chinese Herbal
- Tumor Necrosis Factor-alpha
- tanreqing
- Interleukin-10
- Peroxidase
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Topics |
- Adult
- Aged
- Cytokines
(blood)
- Drug-Related Side Effects and Adverse Reactions
- Drugs, Chinese Herbal
(administration & dosage, adverse effects, therapeutic use)
- Female
- Humans
- Injections
- Interleukin-10
(blood)
- Male
- Middle Aged
- Peroxidase
(blood)
- Pulmonary Disease, Chronic Obstructive
(blood, drug therapy, therapy)
- Treatment Outcome
- Tumor Necrosis Factor-alpha
(blood)
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