New approach to incorporation of boron in tumor-seeking molecules.

Abstract

Cyclic oxonium derivatives of polyhedral boron hydrides have great potential for modification of various types of tumor seeking biomolecules and are very promising starting materials for synthesis of BNCT (boron neutron capture therapy) agents.

• Authors: I B Sivaev, A A Semioshkin, V I Bregadze
• Journal: Applied radiation and isotopes : including data, instrumentation and methods for use in agriculture, industry and medicine (Appl Radiat Isot) Vol. 67 Issue 7-8 Suppl Pg. S91-3 (Jul 2009) ISSN: 1872-9800 [Electronic] England
• PMID: 19375335 (Publication Type: Journal Article, Research Support, Non-U.S. Gov't)

Chemical References

• Boron Compounds
• Radiation-Sensitizing Agents

Topics

• Boron Compounds (chemical synthesis, chemistry, therapeutic use)
• Boron Neutron Capture Therapy (methods)
• Drug Design
• Humans
• Molecular Structure
• Neoplasms (radiotherapy)
• Radiation-Sensitizing Agents (chemical synthesis, chemistry, therapeutic use)