Pharmacotherapy guidelines for the aged by family doctors for the use of family doctors - Part C Special Pharmacology.

Abstract

This article contains the 4th part of the Pharmacotherapy Guidelines for the Aged by Family Doctors for Family Doctors. Part 4 is dedicated to fecal incontinence and chronic constipation. The diagnostic categories are divided according to severity and dysfuntion of bowel and pelvic floor, sphincter and neural control. Therapy is also outlined. Importance is given to patient history, in particular the use and abuse of drugs that stimulate peristalsis and promote constipation. Therapy in the elderly is guided by the maxim: use the most conservative therapy possible, where stool training has considerable importance. Drug therapy based on symptoms can only be recommended when non-drug measures continue to fail. In patients with fecal incontinence: 1) opiates (which reduce colonic motility), 2) loperamide (which has the capacity to dilate the rectum) and 3) anion exchangers which have the capacity to prevent cholonic diarrhea. In patients with chronic obstipation: 1) trial: stool-forming laxatives (ensure intake of sufficient amount of fluids) 2) trial: laxatives with an osmotic effect and 3) trial: stimulating laxatives (beware abuse, do not use in cases of acute abdomen).

• Authors: F W Bergert, D Conrad, K Ehrenthal, J Fessler, J Gross, K Gundermann, B Kluthe, W Lang Heinrich, A Liesenfeld, P G Loew, E Luther, R Pchalek, J Seffrin, A Sterzing, H-J Wolfring, U Zimmermann, Guideline Group Hesse
• Journal: International journal of clinical pharmacology and therapeutics (Int J Clin Pharmacol Ther) Vol. 47 Issue 4 Pg. 223-8 (Apr 2009) ISSN: 0946-1965 [Print] Germany
• PMID: 19356387 (Publication Type: Journal Article, Practice Guideline)

Chemical References

• Laxatives

Topics

• Aged
• Chronic Disease
• Constipation (drug therapy, etiology, therapy)
• Family Practice
• Fecal Incontinence (drug therapy, etiology, therapy)
• Humans
• Laxatives (therapeutic use)
• Practice Patterns, Physicians'