Abstract | AIMS: METHODS: Eighty-six patients with seasonal allergic conjunctivitis were treated with DSCG four times a day, and BF was concomitantly administered twice a day in one eye and FML was administered four times a day in the contralateral eye for 1 week. Ocular signs were scored on a four-graded severity. Patients recorded symptoms using visual analog scale. Patients were asked which concomitant treatment was more suitable for them and scored global evaluation. RESULTS: All subjective symptom scores were decreased in both concomitant treatment groups compared with baseline (P < 0.05). Objective signs were significantly improved with the concomitant use of BF or FML with DSCG (P < 0.05). Neither symptoms nor signs differed significantly between the concomitant use of BF and FML. Fifteen patients selected BF and 29 patients selected FML as the more preferred concomitant eye drops, 42 patients judged no difference in efficacy between the groups. No significant difference was observed in patient's global evaluation between the groups. CONCLUSIONS:
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Authors | Hiroshi Fujishima, Kazumi Fukagawa, Yoji Takano, Mari Tanaka, Shigeki Okamoto, Dai Miyazaki, Jun Yamada, Atsuki Fukushima, Eiichi Uchio, Yayoi Nakagawa |
Journal | Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics
(J Ocul Pharmacol Ther)
Vol. 25
Issue 3
Pg. 265-70
(Jun 2009)
ISSN: 1557-7732 [Electronic] United States |
PMID | 19348602
(Publication Type: Comparative Study, Journal Article, Multicenter Study, Randomized Controlled Trial)
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Chemical References |
- Anti-Allergic Agents
- Anti-Asthmatic Agents
- Benzophenones
- Bromobenzenes
- Ophthalmic Solutions
- Suspensions
- bromfenac
- Cromolyn Sodium
- Fluorometholone
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Topics |
- Administration, Topical
- Adolescent
- Adult
- Aged
- Anti-Allergic Agents
(adverse effects, therapeutic use)
- Anti-Asthmatic Agents
(adverse effects, therapeutic use)
- Benzophenones
(adverse effects, therapeutic use)
- Bromobenzenes
(adverse effects, therapeutic use)
- Conjunctivitis, Allergic
(drug therapy)
- Cromolyn Sodium
(adverse effects, therapeutic use)
- Drug Therapy, Combination
- Female
- Fluorometholone
(adverse effects, therapeutic use)
- Humans
- Male
- Middle Aged
- Ophthalmic Solutions
- Patient Satisfaction
- Suspensions
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