[Acute pancreatitis associated with the administration of ceftriaxone in an adult patient].

Abstract

We report a case of a 35-year-old patient with acute pancreatitis after administration of ceftriaxone. She was given ceftriaxone (2g/day) for 9 days because of diverticulitis of the colon. She was admitted to our hospital again because of epigastralgia 12 days after the first administration of ceftriaxone. Laboratory examination showed markedly elevated serum amylase, and CT scan demonstrated findings consistent with acute pancreatitis, in addition to sludge in the common bile duct and gall bladder, which was not identified before the administration of ceftriaxone. We should be aware of the fact that administration of ceftriaxone sometimes results in the formation of biliary sludge and can cause severe adverse events such as cholecystitis and pancreatitis, not only in children, but also in adult patients.

• Authors: Yumihiko Sasaki, Sachiko Aoki, Kota Aoki, Koichi Achiwa, Tsuyoki Yama, Minoru Kubota, Daisuke Ishikawa, Tetsuya Mizutani, Shin Kunii, Kazumasa Watanabe, Akihiko Okumura
• Journal: Nihon Shokakibyo Gakkai zasshi = The Japanese journal of gastro-enterology (Nihon Shokakibyo Gakkai Zasshi) Vol. 106 Issue 4 Pg. 569-75 (Apr 2009) ISSN: 0446-6586 [Print] Japan
• PMID: 19346727 (Publication Type: English Abstract, Journal Article, Review)

Chemical References

• Ceftriaxone

Topics

• Acute Disease
• Adult
• Ceftriaxone (adverse effects)
• Cholecystitis (chemically induced)
• Female
• Humans
• Pancreatitis (chemically induced)