Abstract | PURPOSE: To assess the long-term visual outcomes and refractive status in patients with diode laser-treated threshold retinopathy of prematurity (ROP), and to investigate the causes of impaired visual function. METHOD: A total of 60 eyes of 30 consecutive patients with diode laser-treated threshold ROP were recalled for assessment at the age of 7 years or more. RESULTS: There were 38 eyes (65.5%) achieving 6/12 or better vision, however, an unfavourable visual outcome (6/60 or worse) occurred in four eyes (6.9%). One eye (1.7%) had unfavourable structural outcome. Of these 60 laser-treated eyes, 46 eyes (77.0%) were myopic, the overall mean spherical equivalent was -3.87 D. Anisometropia (>or=1.5 D) was also noted in 14 patients (46.7%). Strabismus was present in nine patients (30.0%). Perinatal neurological events of intraventricular haemorrhage (IVH) were identified in eight children (26.7%), periventricular leucomalacia (PVL) in eight children (26.7%), and cerebral palsy (CP) in four children (13.3%). There was a statistically significant association of the presence of strabismus with PVL (P=0.002). The presence of anisometropia was a significant risk factor associated with poor visual outcome of 6/15 or worse in laser-treated ROP (P=0.002). CONCLUSION: The majority of patients with diode laser-treated threshold ROP had favourable anatomical and visual outcomes. However, anisometropia, advanced refractive error, strabismus, and perinatal neurological events remain important causes of impaired visual function. Long-term follow-up is very important for early detection and timely treatment of these ocular morbidities.
|
Authors | C-S Yang, A-G Wang, C-S Sung, W-M Hsu, F-L Lee, S-M Lee |
Journal | Eye (London, England)
(Eye (Lond))
Vol. 24
Issue 1
Pg. 14-20
(Jan 2010)
ISSN: 1476-5454 [Electronic] England |
PMID | 19343053
(Publication Type: Journal Article, Research Support, Non-U.S. Gov't)
|
Topics |
- Child
- Female
- Follow-Up Studies
- Gestational Age
- Humans
- Infant, Newborn
- Laser Coagulation
(methods)
- Lasers, Semiconductor
(therapeutic use)
- Male
- Refraction, Ocular
(physiology)
- Retinopathy of Prematurity
(physiopathology, surgery)
- Risk Factors
- Treatment Outcome
- Visual Acuity
(physiology)
|