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[Ocular retention in patients with uveal melanoma managed by a multimodality approach].

AbstractOBJECTIVE:
to analyze ocular survival in eyes with uveal melanoma treated with conservative therapies, in a centre that applies all treatment modalities.
METHODS:
Patients diagnosed with uveal melanoma and treated between September 1990 and April 2007 were included in an historical cohorts study.
RESULTS:
273 patients were included. 193 were treated with conservative treatments (70.69%) and 80 were enucleated as primary treatment. 14 patients were enucleated after conservative treatment (7.2%). Kaplan-Meier survival analysis showed an 88% survival probability of the eye in the first 5 years after conservative treatment and 83% at 10 years.
CONCLUSIONS:
Conservative treatments for uveal melanoma, especially brachitherapy, are safe and effective in relation to tumor control and rate of secondary effects.
AuthorsC García-Alvarez, Y Muiños, M A Saornil, A Almaraz, F López-Lara, J M Frutos, M F Muñoz
JournalArchivos de la Sociedad Espanola de Oftalmologia (Arch Soc Esp Oftalmol) Vol. 84 Issue 3 Pg. 145-9 (Mar 2009) ISSN: 0365-6691 [Print] Spain
Vernacular TitleEstudio de la conservación del globo ocular con un abordaje multiterapéutico en el melanoma uveal.
PMID19340720 (Publication Type: Comparative Study, English Abstract, Journal Article)
Topics
  • Adolescent
  • Adult
  • Aged
  • Aged, 80 and over
  • Brachytherapy
  • Cohort Studies
  • Combined Modality Therapy
  • Eye Enucleation
  • Female
  • Follow-Up Studies
  • Humans
  • Kaplan-Meier Estimate
  • Male
  • Melanoma (diagnosis, mortality, radiotherapy, surgery, therapy)
  • Middle Aged
  • Time Factors
  • Uveal Neoplasms (diagnosis, mortality, radiotherapy, surgery, therapy)

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