Abstract | BACKGROUND: METHODS: RESULTS: At 3 and 12 months, the anti-infective therapy resulted in significant improvements in all clinical parameters (P <0.05). Moreover, the total amount of TNF-alpha was significantly reduced at 3 and 12 months after therapy compared to baseline (P <0.05), paralleling the changes in mean probing depth and bleeding on probing. CONCLUSION: The anti-infective mechanical therapy reduced the crevicular levels of TNF-alpha in sites affected by peri-implantitis over a period of 12 months, and this phenomenon was associated with improvements in clinical parameters.
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Authors | Adriana Cutrim de Mendonça, Vanessa Renata Santos, João Batista César-Neto, Poliana Mendes Duarte |
Journal | Journal of periodontology
(J Periodontol)
Vol. 80
Issue 4
Pg. 693-9
(Apr 2009)
ISSN: 0022-3492 [Print] United States |
PMID | 19335091
(Publication Type: Case Reports, Journal Article, Research Support, Non-U.S. Gov't)
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Chemical References |
- Anti-Infective Agents, Local
- Dental Implants
- Mouthwashes
- Tumor Necrosis Factor-alpha
- chlorhexidine gluconate
- Chlorhexidine
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Topics |
- Aged
- Anti-Infective Agents, Local
(therapeutic use)
- Chlorhexidine
(analogs & derivatives, therapeutic use)
- Debridement
- Dental Implants
(adverse effects)
- Enzyme-Linked Immunosorbent Assay
- Female
- Gingival Crevicular Fluid
(chemistry)
- Humans
- Male
- Middle Aged
- Mouthwashes
(therapeutic use)
- Periodontal Index
- Periodontitis
(drug therapy, etiology, surgery)
- Tumor Necrosis Factor-alpha
(analysis, metabolism)
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