Abstract | BACKGROUND: PATIENTS AND METHODS: RESULTS: Ninety women were enrolled of whom 89 (median age, 54 years) received a median of 6 cycles (range 1 to 9). With a median 38 months'follow-up, median progression-free survival was 28 months (95% lower confidence interval, 24 months) in 60 patients with stage III-IV disease. The overall response rate for 20 patients was 45%. Neutropenia was the most common (67%) grade 3/4 toxicity. Major grade 3/4 nonhaematological toxicities were gastrointestinal toxicities (< or = 11%) and fatigue (8%). No grade 3/4 neurotoxicity was observed. CONCLUSION:
|
Authors | Daisuke Aoki, Yoh Watanabe, Toshiko Jobo, Kimio Ushijima, Kiyoshi Hasegawa, Nobuyuki Susumu, Nao Suzuki, Rui Aoki, Seiji Isonishi, Satoru Sagae, Bunpei Ishizuka, Toshiharu Kamura, Yasuhiro Udagawa, Hiroshi Hoshiai, Yasuo Ohashi, Kazunori Ochiai, Kiichiro Noda |
Journal | Anticancer research
(Anticancer Res)
Vol. 29
Issue 2
Pg. 561-6
(Feb 2009)
ISSN: 0250-7005 [Print] Greece |
PMID | 19331203
(Publication Type: Clinical Trial, Phase II, Journal Article, Multicenter Study)
|
Chemical References |
- Taxoids
- Docetaxel
- Cisplatin
|
Topics |
- Adult
- Aged
- Antineoplastic Combined Chemotherapy Protocols
(administration & dosage, adverse effects)
- Cisplatin
(administration & dosage, adverse effects)
- Docetaxel
- Female
- Humans
- Japan
- Middle Aged
- Neoplasm Staging
- Ovarian Neoplasms
(drug therapy, pathology)
- Taxoids
(administration & dosage, adverse effects)
|