Abstract | AIM: MATERIALS AND METHODS: NCI-H2087 cells were trypsinized and 100 x 10(6) cells were incubated in a sealed fermenter overnight. Samples from the headspace of the culture vessel were collected with simultaneous preconcentration by adsorption on solid sorbents and subsequently thermodesorbed for analysis by gas chromatography mass spectrometry (GC-MS). RESULTS: CONCLUSION: Our findings demonstrate that certain compounds can be cancer cell derived and thus may be indicative of the presence of a tumor. Some compounds were not released but seem to be consumed by cancer cells.
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Authors | Andreas Sponring, Wojciech Filipiak, Tomas Mikoviny, Clemens Ager, Jochen Schubert, Wolfram Miekisch, Anton Amann, Jakob Troppmair |
Journal | Anticancer research
(Anticancer Res)
Vol. 29
Issue 1
Pg. 419-26
(Jan 2009)
ISSN: 0250-7005 [Print] Greece |
PMID | 19331181
(Publication Type: Journal Article, Research Support, Non-U.S. Gov't)
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Chemical References |
- Volatile Organic Compounds
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Topics |
- Cell Line, Tumor
- Gas Chromatography-Mass Spectrometry
- Humans
- Lung Neoplasms
(metabolism)
- Volatile Organic Compounds
(analysis, metabolism)
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