| Abstract | OBJECTIVE: To describe a case of ovarian luteinized thecoma, a rare ovarian neoplasm, which is only the 26th reported case associated with sclerosing peritonitis. DESIGN: Case report. SETTING: NYU Fertility Center and Memorial Hospital for Cancer and Allied Diseases, New York. PATIENT(S): A 17-year-old woman presenting with a large pelvic mass and abdominal pain. INTERVENTION(S): Conservative surgical treatment with laparotomy, unilateral salpingooophorectomy, and biopsy of contralateral ovary. Gonadotropin-releasing hormone agonist suppression. Ovarian hyperstimulation with oocyte retrieval/freezing to preserve biologic fertility. MAIN OUTCOME MEASURE(S): Response to conservative therapy and oocyte cryopreservation as a method of fertility preservation. RESULT(S): At laparotomy, obvious unilateral ovarian involvement was present, and a left salpingoophorectomy was performed. Biopsy of the contralateral ovary confirmed bilateral disease. The initial pathological review was complicated by extensive ovarian edema. The patient was treated with gonadotropin-releasing hormone agonist suppression plus intermittent estradiol supplementation. When she became intolerant of hormone therapy and when removal of the remaining ovary became a possibility, she underwent ovarian hyperstimulation; oocyte retrieval and freezing were performed to preserve her biologic fertility. Thirty-eight eggs were obtained. CONCLUSION(S): Surgically diagnosed luteinized thecoma can be managed medically. Oocyte cryopreservation as a means of fertility preservation should be considered in young women with this diagnosis who are at risk for bilateral gonad removal. |
| Authors | Nicole Noyes, Rosanna C Perretta, M Elizabeth Fino, Theodore Matulewicz, Richard Barakat
(Affiliation: NYU Fertility Center, Department of Obstetrics and Gynecology, New York University School of Medicine, 660 First Avenue, Fifth Floor, New York, NY 10016, USA.)
|
| Journal | Fertility and sterility
(Fertil Steril)
Vol. 92
Issue 1
Pg. 393.e11-4
(Jul 2009)
ISSN: 1556-5653 [Electronic] United States |
| PMID | 19327766
(Publication Type: Case Reports, Journal Article)
|
| Chemical References |
- Gonadotropin-Releasing Hormone
- Estradiol
|
| Topics |
- Adolescent
- Cryopreservation
(methods)
- Estradiol
(therapeutic use)
- Female
- Gonadotropin-Releasing Hormone
(agonists)
- Humans
- Oocyte Retrieval
(methods)
- Oocytes
(cytology)
- Organ Preservation
(methods)
- Ovarian Neoplasms
(complications, drug therapy, pathology)
- Ovulation Induction
(methods)
- Peritonitis
(complications)
- Thecoma
(complications, drug therapy, pathology)
|
