Abstract |
Three patients with vaginal rhabdomyosarcoma and residual vaginal disease following surgery and chemotherapy have been treated using high dose irradiation with vaginal moulds loaded with iridium-192. These patients remain well and disease-free seven years, 30 months and 18 months after their initial presentations. This paper describes a technique for local vaginal irradiation with individualized vaginal moulds made using a rapid-setting silastic foam impression and loaded with a single plane of iridium wires. Details of the dosimetry are also included.
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Authors | M E O'Connell, P J Hoskin, W P Mayles, T J McElwain, A Barrett |
Journal | Clinical oncology (Royal College of Radiologists (Great Britain))
(Clin Oncol (R Coll Radiol))
Vol. 3
Issue 4
Pg. 236-9
(Jul 1991)
ISSN: 0936-6555 [Print] England |
PMID | 1931767
(Publication Type: Case Reports, Journal Article)
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Chemical References |
- Iridium Radioisotopes
- Dactinomycin
- Vincristine
- Doxorubicin
- Cyclophosphamide
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Topics |
- Antineoplastic Combined Chemotherapy Protocols
(therapeutic use)
- Brachytherapy
(instrumentation, methods)
- Combined Modality Therapy
- Cyclophosphamide
(administration & dosage)
- Dactinomycin
(administration & dosage)
- Doxorubicin
(administration & dosage)
- Equipment Design
- Female
- Humans
- Infant
- Iridium Radioisotopes
(administration & dosage)
- Radiotherapy Dosage
- Rhabdomyosarcoma
(drug therapy, radiotherapy)
- Vagina
(radiation effects)
- Vaginal Neoplasms
(drug therapy, radiotherapy)
- Vincristine
(administration & dosage)
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