Treatment of inflammatory facial acne with 1,450-nm diode laser in type IV to V Asian skin using an optimal combination of laser parameters.

Abstract

BACKGROUND:

The 1,450-nm diode laser is effective for the treatment of inflammatory acne, but there is a significant risk of postinflammatory hyperpigmentation (PIH) in Asian skin.

OBJECTIVE:

To determine whether lower fluence and shorter cooling duration of the 1,450-nm diode laser improve acne effectively with minimal PIH in darker skin.

MATERIALS AND METHODS:

Twenty-six subjects (skin phototypes IV-V) with inflammatory facial acne received four treatments using the 1,450-nm diode laser with 6-mm spot size 3 to 4 weeks apart. We used three passes with a fluence of 8 J/cm(2) with dynamic cooling of 25 ms to minimize PIH. Serial blinded assessment of acne lesion counts and sebum measurement were evaluated before and up to 6 months after treatment.

RESULTS:

Four weeks and 6 months after the last treatment, reduction of mean acne lesions was 29% (p<.01) and 40% (p<.03), respectively, from baseline in the group with moderate acne. Significant improvements of sebum production were noted. Four episodes of temporary PIH (3.8%) were observed out of all treatment sessions.

CONCLUSION:

Use of multiple passes of a 1,450-nm diode laser with lower fluence and shorter dynamic cooling device retains its therapeutic efficacy with substantial reduction of PIH for moderate acne.

• Authors: Chi K Yeung, Samantha Y Shek, Carol S Yu, Taro Kono, Henry H Chan
• Journal: Dermatologic surgery : official publication for American Society for Dermatologic Surgery [et al.] (Dermatol Surg) Vol. 35 Issue 4 Pg. 593-600 (Apr 2009) ISSN: 1524-4725 [Electronic] United States
• PMID: 19309346 (Publication Type: Journal Article)

Topics

• Acne Vulgaris (complications, radiotherapy)
• Adolescent
• Adult
• Asian People
• Face
• Female
• Humans
• Hyperpigmentation (etiology, prevention & control)
• Laser Therapy (adverse effects)
• Male
• Young Adult