Abstract | BACKGROUND: To compare the preoperative clinical symptoms and associated conditions and findings in operations in age- and sex-matched patients with primary hyperparathyroidism (PHPT) living in the two different regions of the world to determine whether PHPT differs in various countries. METHODS: Fifty-two patients from Bursa, Turkey were matched with 52 age and sex matched patients from San Francisco, USA. Patients' preoperative symptoms, biochemical and radiologic findings and surgical procedures were documented. RESULTS: More patients in the American Group (15%) had preoperatively persistant or recurrent hyperparathyroidism, P = 0.016. Serum parathyroid hormone levels were higher in Turkish group (546 +/- 75.33 pg/mL) than in American group (146 +/- 75.33 pg/mL). More Turkish patients had osteoporosis (P < 0.05). The size of parathyroid adenomas was significantly greater in Turkish patients (25.2 +/- 1.18 mm) than in American patients (17.5 +/- 1.18 mm), P < 0.001. CONCLUSIONS:
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Authors | Turkay Kirdak, Quan-Yang Duh, Electron Kebebew, Orlo Herrick Clark |
Journal | American journal of surgery
(Am J Surg)
Vol. 198
Issue 2
Pg. 188-92
(Aug 2009)
ISSN: 1879-1883 [Electronic] United States |
PMID | 19306981
(Publication Type: Comparative Study, Journal Article, Research Support, Non-U.S. Gov't)
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Chemical References |
- Parathyroid Hormone
- Phosphorus
- Creatinine
- Alkaline Phosphatase
- Calcium
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Topics |
- Adenoma
(pathology, surgery)
- Adult
- Aged
- Alkaline Phosphatase
(blood)
- Anesthesia, General
(statistics & numerical data)
- Anesthesia, Local
(statistics & numerical data)
- Calcium
(blood, urine)
- California
(epidemiology)
- Creatinine
(blood)
- Female
- Humans
- Hyperparathyroidism, Primary
(epidemiology, surgery)
- Male
- Middle Aged
- Multiple Endocrine Neoplasia
(epidemiology)
- Osteoporosis
(diagnostic imaging, epidemiology)
- Parathyroid Hormone
(blood)
- Parathyroid Neoplasms
(pathology, surgery)
- Parathyroidectomy
- Phosphorus
(blood)
- Radiography
- Retrospective Studies
- Turkey
(epidemiology)
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