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Intriguing response to azacitidine in a patient with juvenile myelomonocytic leukemia and monosomy 7.

AuthorsIngrid Furlan, Christiane Batz, Christian Flotho, Brigitte Mohr, Michael Lübbert, Meinolf Suttorp, Charlotte M Niemeyer
JournalBlood (Blood) Vol. 113 Issue 12 Pg. 2867-8 (Mar 19 2009) ISSN: 1528-0020 [Electronic] United States
PMID19299654 (Publication Type: Case Reports, Letter, Research Support, Non-U.S. Gov't, Comment)
Chemical References
  • Antimetabolites, Antineoplastic
  • Neoplasm Proteins
  • Protein Precursors
  • Calcitonin
  • Azacitidine
Topics
  • Antimetabolites, Antineoplastic (pharmacology, therapeutic use)
  • Azacitidine (pharmacology, therapeutic use)
  • Bone Marrow Cells (ultrastructure)
  • Calcitonin (genetics)
  • Chromosomes, Human, Pair 7
  • Clone Cells (ultrastructure)
  • Combined Modality Therapy
  • CpG Islands
  • DNA Methylation (drug effects)
  • Genes, ras
  • Hematopoietic Stem Cell Transplantation
  • Humans
  • Infant
  • Leukemia, Myelomonocytic, Juvenile (drug therapy, genetics, surgery)
  • Male
  • Monosomy
  • Neoplasm Proteins (genetics)
  • Point Mutation
  • Promoter Regions, Genetic
  • Protein Precursors (genetics)
  • Remission Induction

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