Abstract |
Based on findings from the Prepubertal Testis Tumor Registry by the Urologic Section of the American Academy of Pediatrics and collaborative data in the literature, a modern algorithm for the surgical management of prepubertal testis tumors is presented. Following testicular surgery, patients with universally benign tumors, such as teratoma, may be released from oncological follow-up. Children with stage I yolk sac tumors should be monitored closely with periodic AFP tumor marker evaluation and imaging according to the primary dissemination (e.g., ultrasound, chest x-ray, and computed tomography). Patients with recurrent or metastatic yolk sac tumors should be treated with platinum-based chemotherapy and appropriate follow-up. Retroperitoneal lymph node dissection is not recommended except for patients with residual retroperitoneal masses following chemotherapy. Aggressive treatment is warranted for metastatic Sertoli cell and metastatic undifferentiated stromal tumors.
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Authors | J Steffens, A Treiyer, G Calaminus |
Journal | Der Urologe. Ausg. A
(Urologe A)
Vol. 48
Issue 4
Pg. 359-63
(Apr 2009)
ISSN: 1433-0563 [Electronic] Germany |
Vernacular Title | Präpubertäre Hodentumoren : Diagnose, Therapie und Nachbeobachtung. |
PMID | 19280171
(Publication Type: English Abstract, Journal Article, Review)
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Topics |
- Child
- Humans
- Male
- Medical Oncology
(trends)
- Pediatrics
(trends)
- Testicular Neoplasms
(diagnosis, therapy)
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