Recurrence of 131I-induced thyroid storm after discontinuing glucocorticoid therapy.

Abstract	A 19-year-old woman with Graves' disease developed thyroid storm 8 days after radioactive iodine therapy. The clinical manifestations of thyroid storm promptly improved after treatment with large doses of propylthiouracil, potassium iodide, propranolol hydrochloride, and dexamethasone. Four days after discontinuing dexamethasone, the syndrome recurred and was corrected by reinstitution of the glucocorticoid. We conclude that dexamethasone was an important adjunct for treating thyroid storm and was effective mainly by reducing peripheral triiodothyronine production.
Authors	A I Kidess, R H Caplan, R H Reynertson, G Wickus
Journal	Wisconsin medical journal (Wis Med J) Vol. 90 Issue 8 Pg. 463-5 (Aug 1991) ISSN: 0043-6542 [Print] United States
PMID	1926884 (Publication Type: Case Reports, Journal Article)
Chemical References	Iodine Radioisotopes Propylthiouracil Dexamethasone Propranolol
Topics	Adult Dexamethasone (administration & dosage, therapeutic use) Drug Therapy, Combination Female Humans Infant Iodine Radioisotopes (adverse effects) Propranolol (administration & dosage, therapeutic use) Propylthiouracil (administration & dosage, therapeutic use) Recurrence Thyroid Crisis (drug therapy, etiology)

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