Recent progress in
wound management is mainly in terms of physiological support for healing. Since
infections delay healing and worsen
scar formation, there is a desire to achieve closure as soon as possible. The main goals of
wound care are prevention of
infection, maintenance of a moist environment, protection of the
wound and achievement of minimum
scar formation. In this study were investigated in a clinical model the effects of a new
chitin nanofibrils-based gel on the rate and quality of wound healing.
Chitin has some unusual properties which accelerate the healing of
wounds in humans. The main biochemical activities of
chitin and
chitosan-based materials are: polymorphonuclear cell activation, fibroblast activation,
cytokine production, giant cell migration and stimulation of
type IV collagen synthesis. The results of this clinical study confirm that
chitin nanofibrils-based gel promotes rapid and physiological healing of different types of
wounds. Moreover, it seems to prevent hypertrophic
scarring and
keloid scarring.