Endometrial carcinoma with choriocarcinomatous differentiation: a case report and review of the literature.

Abstract

BACKGROUND:

Choriocarcinomas unrelated to pregnancy, teratomas, or germ cell tumors have been found in the stomach, lungs, colon, esophagus, bladder, breast, renal pelvis and other sites.

CASE:

We present a case of a 58-year-old woman with endometrial carcinoma with choriocarcinomatous differentiation. She received surgery and chemotherapy for endometrial adenocarcinoma. However, a metastatic tumor of choriocarcinomatous element appeared at the vaginal cuff 9 months after surgery. Additional chemotherapy for choriocarcinoma resulted in a decrease in the serum hCG and the tumor regressed. Fifty months following surgery, she is alive without disease.

CONCLUSION:

Treatment and follow-up must be performed not only for the adenocarcinoma element but also for the choriocarcinoma element in patients presenting with endometrial carcinoma with choriocarcinomatous differentiation.

• Authors: Takashi Yamada, Hiroshi Mori, Masanori Kanemura, Masahide Ohmichi, Yuro Shibayama
• Journal: Gynecologic oncology (Gynecol Oncol) Vol. 113 Issue 2 Pg. 291-4 (May 2009) ISSN: 1095-6859 [Electronic] United States
• PMID: 19232701 (Publication Type: Case Reports, Journal Article)

Topics

• Adenocarcinoma (drug therapy, pathology, surgery)
• Choriocarcinoma (drug therapy, pathology, surgery)
• Endometrial Neoplasms (drug therapy, pathology, surgery)
• Female
• Humans
• Middle Aged