HOMEPRODUCTSSERVICESCOMPANYCONTACTFAQResearchDictionaryPharmaMobileSign Up FREE or Login

Risks and benefits of generic antiepileptic drugs.

AbstractINTRODUCTION:
In most therapeutic areas, prescribing generic drugs seems to lower costs without sacrificing efficacy. The use of generic drugs for treating epilepsy may, however, be more controversial.
MATERIALS AND METHODS:
A systematic review of the literature on generic antiepileptic drugs has been carried out based primarily on a bibliographical search in the Medline database.
RESULTS:
Published studies are usually of a descriptive nature and are sometimes based on generic drugs that were approved in times when regulatory agency requirements were not as strict as they are now. Experts claim that a change in pharmaceutical formulations could cause seizure recurrence in cases that had been successfully controlled in the past, with severe effects on patients. Meanwhile, several health organizations have provided inconsistent recommendations on the use of generic antiepileptic drugs.
CONCLUSION:
In order to obtain scientific evidence on the potential risks and benefits of interchanging branded and generic antiepileptic drugs, high methodological comparative studies are necessary. These studies could bring consensus about the role of generic drugs for treating epilepsy.
AuthorsJuan Gómez-Alonso, Andrés M Kanner, José Luis Herranz, Albert Molins, Antonio Gil-Nagel
JournalThe neurologist (Neurologist) Vol. 14 Issue 6 Suppl 1 Pg. S66-72 (Nov 2008) ISSN: 1074-7931 [Print] United States
PMID19225372 (Publication Type: Journal Article, Research Support, Non-U.S. Gov't, Review)
Chemical References
  • Anticonvulsants
  • Drugs, Generic
Topics
  • Anticonvulsants (adverse effects, economics, therapeutic use)
  • Drugs, Generic (adverse effects, economics, therapeutic use)
  • Humans
  • Risk

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.
Realize the full power of the drug-disease research network!


Choose Username:
Email:
Password:
Verify Password: