Abstract | PURPOSE: Peri-implant dehiscence defects occur frequently after dental implant placement. Various graft materials and techniques are proposed for treatment. In this study, an injectable calcium phosphate cement (Augmentech, Wetzlar, Germany) applied to a peri-implant defect was investigated. MATERIALS AND METHODS: Standardized buccal dehiscence defects (5.8 x 3.8 mm) were surgically created after implant site preparation in the right proximal tibiae of 5 beagle dogs. Fifteen stepped cylindrical implants (13 x 3.8 mm diameter) were inserted (3 per dog), and Augmentech injectable calcium phosphate cement was injected into the dehiscences. The bone at the distal side of the implant was left intact to serve as a control. Postsurgically, each dog received double staining of 2 fluorescent labels for estimation of bone cell activity at baseline and after 11 weeks of healing. The animals were sacrificed after 12 weeks. Dissected blocks were processed for histologic, histomorphometric, and fluorescence microscopic analysis, ie, percentage of bone-to-implant contact ( BIC) and percentage linear bone height (LBH) were measured. Student t and Mann Whitney U tests were used for statistical analysis (P < .05). RESULTS: CONCLUSION:
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Authors | Volkan Arisan, Tayfun Ozdemir, Ata Anil, John A Jansen, Kürsat Ozer |
Journal | The International journal of oral & maxillofacial implants
(Int J Oral Maxillofac Implants)
2008 Nov-Dec
Vol. 23
Issue 6
Pg. 1053-62
ISSN: 0882-2786 [Print] United States |
PMID | 19216274
(Publication Type: Journal Article)
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Chemical References |
- Bone Cements
- Bone Substitutes
- Calcium Phosphates
- Dental Implants
- Fluorescent Dyes
- calcium phosphate
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Topics |
- Animals
- Bone Cements
(therapeutic use)
- Bone Regeneration
(physiology)
- Bone Remodeling
(physiology)
- Bone Substitutes
(administration & dosage, therapeutic use)
- Calcium Phosphates
(administration & dosage, therapeutic use)
- Dental Implants
(adverse effects)
- Dogs
- Fluorescent Dyes
- Guided Tissue Regeneration
(methods)
- Haversian System
(pathology)
- Injections
- Male
- Microscopy, Fluorescence
- Osseointegration
(physiology)
- Osteoclasts
(pathology)
- Osteogenesis
(physiology)
- Surgical Wound Dehiscence
(surgery)
- Tibia
(pathology, surgery)
- Wound Healing
(physiology)
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