Abstract | OBJECTIVE: METHOD: Thirty consecutive patients with a complex anal fistula underwent glue instillation after an 8 week period of seton drainage. Cure was defined as complete closure of any secondary opening, absence of fistula seepage, and no abscess formation. RESULTS: The mean age of the patients (15 males) was 40.5 (range, 22.8-69.1) years. The mean duration of follow-up was 11.7 (range, 0.2-33.5) months. Complete closure of the fistula was achieved in 17 patients at 1 month but in two patients a delayed abscess occurred. At the end of follow-up, 15 (50%) patients were considered to have been cured. The success rate was no different in cases of Crohn's disease or when postoperative antibiotic therapy was given. There was, however, a significant difference in success following regional vs general anaesthesia (68.4 vs 18.2% success, P = 0.02). CONCLUSION:
Fibrin glue cured 50% of our first 30 patients, and regional anaesthesia was predictive of success.
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Authors | V de Parades, H Safa Far, I Etienney, J-D Zeitoun, P Atienza, P Bauer |
Journal | Colorectal disease : the official journal of the Association of Coloproctology of Great Britain and Ireland
(Colorectal Dis)
Vol. 12
Issue 5
Pg. 459-63
(May 2010)
ISSN: 1463-1318 [Electronic] England |
PMID | 19210300
(Publication Type: Journal Article)
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Chemical References |
- Fibrin Tissue Adhesive
- Tissue Adhesives
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Topics |
- Adult
- Aged
- Combined Modality Therapy
- Drainage
- Female
- Fibrin Tissue Adhesive
(administration & dosage)
- Humans
- Male
- Middle Aged
- Prospective Studies
- Rectal Fistula
(surgery, therapy)
- Tissue Adhesives
(administration & dosage)
- Young Adult
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