Abstract | BACKGROUND AND OBJECTIVE: To compare the analgesic effectiveness and aesthetic appearance associated with topical, subconjunctival, and peribulbar anesthesia for intravitreal bevacizumab injection. PATIENTS AND METHODS: RESULTS: Median injection-related pain score was significantly lower in the peribulbar group compared with the topical and subconjunctival groups (P < .05). Median entire procedure pain score was significantly higher in the peribulbar group compared with the topical and subconjunctival groups (P < .05). The median extent of subconjunctival hemorrhage was significantly lower in the topical group compared with the other groups (P < .05). CONCLUSION: Among the three anesthetic techniques, peribulbar anesthesia was associated with greater effectiveness in controlling injection-related pain but was least effective in controlling entire procedure pain. There was no significant difference in pain scores between the topical and subconjunctival groups, and topical anesthesia was associated with less subconjunctival hemorrhage.
|
Authors | Léssia P Cintra, Levy R Lucena, José A Da Silva, Rogério A Costa, Ingrid U Scott, Rodrigo Jorge |
Journal | Ophthalmic surgery, lasers & imaging : the official journal of the International Society for Imaging in the Eye
(Ophthalmic Surg Lasers Imaging)
2009 Jan-Feb
Vol. 40
Issue 1
Pg. 13-8
ISSN: 1542-8877 [Print] United States |
PMID | 19205490
(Publication Type: Comparative Study, Journal Article, Randomized Controlled Trial)
|
Chemical References |
- Anesthetics, Local
- Angiogenesis Inhibitors
- Antibodies, Monoclonal
- Antibodies, Monoclonal, Humanized
- Bevacizumab
- Lidocaine
- proxymetacaine
- Propoxycaine
|
Topics |
- Analgesia
(methods)
- Anesthesia, Local
(methods)
- Anesthetics, Local
(administration & dosage)
- Angiogenesis Inhibitors
(administration & dosage)
- Antibodies, Monoclonal
(administration & dosage)
- Antibodies, Monoclonal, Humanized
- Bevacizumab
- Female
- Humans
- Injections
- Lidocaine
(administration & dosage)
- Male
- Middle Aged
- Pain
(diagnosis, prevention & control)
- Pain Measurement
- Propoxycaine
(administration & dosage)
- Vitreous Body
|