HOMEPRODUCTSCOMPANYCONTACTFAQResearchDictionaryPharmaSign Up FREE or Login

Improvement in iron deficiency anemia through therapy with ferric ammonium citrate and vitamin C and the effects of aerobic exercise.

Abstract
In 781 female college students, there were 41 cases of iron deficiency anemia, 209 of latent iron deficiency, 3 of other anemias, and 528 normal cases. Fifty-four volunteers recruited from the iron deficiency anemia and severe latent iron deficiency groups were randomly divided into 4 study groups. Groups I and III received 500 mg of vitamin C daily, and groups II and IV received ferric ammonium citrate (FeAC; equivalent to 6 mg iron) in addition to vitamin C for 9 weeks. Groups I and II were loaded by aerobic exercise at 50% VO2 max. Significant differences between groups were noted in serum ferritin (SF) in III/IV, hematocrit (Ht) in II/III and III/IV, and reticulocytes (RET) in I/II, I/IV, and III/IV. Hemoglobin (Hb) and other iron-related blood indices tended to normalize in groups II and IV when compared with the pre-values. VO2 max was elevated in groups I and II regardless of iron treatment, but was augmented more in group II than group I.
AuthorsM Taniguchi, H Imamura, T Shirota, H Okamatsu, Y Fujii, M Toba, F Hashimoto
JournalJournal of nutritional science and vitaminology (J Nutr Sci Vitaminol (Tokyo)) Vol. 37 Issue 2 Pg. 161-71 (Apr 1991) ISSN: 0301-4800 [Print] Japan
PMID1919803 (Publication Type: Clinical Trial, Journal Article, Randomized Controlled Trial)
Chemical References
  • Ferric Compounds
  • Hemoglobins
  • Quaternary Ammonium Compounds
  • Iron
  • Ascorbic Acid
  • Oxygen
  • ferric ammonium citrate
Topics
  • Adolescent
  • Adult
  • Anemia, Hypochromic (blood, drug therapy, physiopathology)
  • Ascorbic Acid (therapeutic use)
  • Drug Therapy, Combination
  • Exercise
  • Female
  • Ferric Compounds (therapeutic use)
  • Hemoglobins (metabolism)
  • Humans
  • Iron (blood)
  • Nutritional Status
  • Oxygen (metabolism)
  • Quaternary Ammonium Compounds (therapeutic use)

Join CureHunter, for free Research Interface BASIC access!

Take advantage of free CureHunter research engine access to explore the best drug and treatment options for any disease. Find out why thousands of doctors, pharma researchers and patient activists around the world use CureHunter every day.
Realize the full power of the drug-disease research graph!


Choose Username:
Email:
Password:
Verify Password:
Enter Code Shown: