Abstract | BACKGROUND: Little is known about the relative efficacy of high- protein vs. conventional diet plans that include partial meal replacements on body fat loss in obese subjects with metabolic syndrome. OBJECTIVE: DESIGN: In a 12-week, double-blind study, we randomised 75 participants to either the HP- or the C-plan group. We recorded key metrics at 0 and 12 weeks. RESULTS: The overall mean weight loss was 5 kg in the HP-plan group and 4.9 kg in the C-plan group (p = 0.72). Truncal fat mass decreased 1.6 kg in the HP-plan group (p < 0.05) and 1.5 kg in the C-plan group (p < 0.05), while whole body fat mass decreased 2.5 kg in the HP-plan group (p < 0.05) and 2.3 kg in the C-plan group (p < 0.05). Between-group losses did not differ significantly for truncal (p = 0.52) or whole body (p = 0.77) fat mass. Among subjects with > or = 70% dietary compliance, however, truncal and whole body fat mass decreased more in the HP-plan group (Delta 2.2 kg and Delta 3.5 kg respectively) than in the C-plan group (Delta 1.3 kg and Delta 2.3 [corrected] kg respectively) (p < 0.05). CONCLUSION: The HP- and C-plans had a similar effect on weight and abdominal fat reduction, but the HP-plan was more effective in reducing body fat among compliant subjects.
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Authors | K Lee, J Lee, W K Bae, J K Choi, H J Kim, B Cho |
Journal | International journal of clinical practice
(Int J Clin Pract)
Vol. 63
Issue 2
Pg. 195-201
(Feb 2009)
ISSN: 1742-1241 [Electronic] India |
PMID | 19196357
(Publication Type: Journal Article, Randomized Controlled Trial, Research Support, Non-U.S. Gov't)
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Chemical References |
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Topics |
- Abdominal Fat
(pathology)
- Adiposity
- Body Mass Index
- Body Weight
(physiology)
- Caloric Restriction
(methods)
- Diet, Reducing
(methods)
- Dietary Proteins
(administration & dosage)
- Double-Blind Method
- Female
- Humans
- Male
- Metabolic Syndrome
(complications, pathology)
- Middle Aged
- Obesity
(complications, diet therapy, pathology)
- Patient Compliance
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