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Plant metabolites. New compounds and anti-inflammatory activity of Uncaria tomentosa.

Abstract
Bioassay-directed fractionation of the anti-inflammatory extracts of Uncaria tomentosa, using the carrageenan-induced edema in rat paw, has led to the isolation of a new quinovic acid glycoside 7 as one of the active principles. Furthermore, a new triterpene 8 was isolated as its methyl ester. The structures were elucidated by spectral and chemical studies.
AuthorsR Aquino, V De Feo, F De Simone, C Pizza, G Cirino
JournalJournal of natural products (J Nat Prod) 1991 Mar-Apr Vol. 54 Issue 2 Pg. 453-9 ISSN: 0163-3864 [Print] United States
PMID1919590 (Publication Type: Journal Article)
Chemical References
  • Anti-Inflammatory Agents, Non-Steroidal
  • Triterpenes
Topics
  • Animals
  • Anti-Inflammatory Agents, Non-Steroidal (isolation & purification)
  • Magnetic Resonance Spectroscopy
  • Male
  • Molecular Structure
  • Plants, Medicinal (chemistry)
  • Rats
  • Rats, Inbred Strains
  • Triterpenes (isolation & purification, pharmacology)

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