Abstract | BACKGROUND: MATERIALS AND METHODS: RESULTS: The average N-ERC ratio, determined by dividing the N-ERC levels following chemotherapy by those prior to chemotherapy, in the partial response (PR) group was significantly lower than that of the stable disease (SD)/progressive disease (PD) group. In contrast, the average OPN ratio, determined by dividing the OPN levels following chemotherapy by those prior to chemotherapy, in the PR group was not statistically different from that of the SD/PD group. CONCLUSION: N-ERC/ mesothelin is considered as relevant in monitoring chemotherapeutic response in patients with mesothelioma.
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Authors | Ken Tajima, Michihiro Hirama, Kazu Shiomi, Toshiji Ishiwata, Masataka Yoshioka, Akihiko Iwase, Shinichiro Iwakami, Mariko Yamazaki, Michie Toba, Kazunori Tobino, Koji Sugano, Masako Ichikawa, Yoshiaki Hagiwara, Kazuhisa Takahashi, Okio Hino |
Journal | Anticancer research
(Anticancer Res)
2008 Nov-Dec
Vol. 28
Issue 6B
Pg. 3933-6
ISSN: 0250-7005 [Print] Greece |
PMID | 19192652
(Publication Type: Journal Article, Research Support, Non-U.S. Gov't)
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Chemical References |
- Biomarkers, Tumor
- GPI-Linked Proteins
- Membrane Glycoproteins
- Osteopontin
- Mesothelin
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Topics |
- Aged
- Antineoplastic Combined Chemotherapy Protocols
(therapeutic use)
- Biomarkers, Tumor
(blood)
- Enzyme-Linked Immunosorbent Assay
- Female
- GPI-Linked Proteins
- Humans
- Male
- Membrane Glycoproteins
(blood)
- Mesothelin
- Mesothelioma
(blood, drug therapy)
- Middle Aged
- Osteopontin
(blood)
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