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Increased thymidylate synthetase activity in 5-fluorodeoxyuridine-resistant Novikoff hepatoma cells.

AuthorsD S Wilkinson, L P Solomonson, J G Cory
JournalProceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.) (Proc Soc Exp Biol Med) Vol. 154 Issue 3 Pg. 368-71 (Mar 1977) ISSN: 0037-9727 [Print] United States
PMID191843 (Publication Type: Journal Article, Research Support, U.S. Gov't, P.H.S.)
Chemical References
  • Floxuridine
  • Methyltransferases
  • Thymidylate Synthase
  • Thymidine Kinase
  • Nucleotidases
  • Adenosine Triphosphatases
Topics
  • Adenosine Triphosphatases (metabolism)
  • Carcinoma, Hepatocellular (enzymology)
  • Cell Line
  • Drug Resistance
  • Floxuridine (pharmacology)
  • Liver Neoplasms
  • Methyltransferases (metabolism)
  • Neoplasms, Experimental (enzymology)
  • Nucleotidases (metabolism)
  • Thymidine Kinase (deficiency)
  • Thymidylate Synthase (antagonists & inhibitors, metabolism)

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