Cytosine arabinoside chemotherapy for acute megakaryocytic leukemia in a cat.

Abstract

Myeloproliferative disease in a cat was characterized by severe, nonregenerative anemia, circulating blast cells, and proliferation of bizarre megakaryoblasts in the bone marrow. The number of circulating platelets was markedly higher than normal at initial examination. Chemotherapy with cytosine arabinoside was successful in inducing complete remission and maintaining survival for 122 days.

• Authors: T A Hamilton, W B Morrison, D B DeNicola
• Journal: Journal of the American Veterinary Medical Association (J Am Vet Med Assoc) Vol. 199 Issue 3 Pg. 359-61 (Aug 01 1991) ISSN: 0003-1488 [Print] United States
• PMID: 1917643 (Publication Type: Case Reports, Journal Article, Research Support, Non-U.S. Gov't)

Chemical References

• Cytarabine

Topics

• Animals
• Biopsy (veterinary)
• Bone Marrow (pathology)
• Cat Diseases (drug therapy)
• Cats
• Cytarabine (therapeutic use)
• Leukemia, Megakaryoblastic, Acute (drug therapy, veterinary)
• Male