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Medullary thyroid carcinoma presenting as rectangular cell type on fine-needle aspiration.

Abstract
Medullary thyroid carcinoma typically presents as dyscohesive plasmacytoid, spindled, or polygonal cells on fine-needle aspiration smears. We recently encountered a case of sporadic medullary thyroid carcinoma that presented as a hypercellular aspirate composed of cohesive aggregates of rectangle-shaped cells. The case was mistakenly reported as a hypercellular follicular neoplasm on cytology. Subsequent thyroidectomy revealed medullary carcinoma. We draw attention to this distinctive rectangular cell type as an additional morphology for medullary thyroid carcinoma.
AuthorsAndrew M Schreiner, Grace C H Yang
JournalDiagnostic cytopathology (Diagn Cytopathol) Vol. 37 Issue 3 Pg. 213-6 (Mar 2009) ISSN: 1097-0339 [Electronic] United States
PMID19156827 (Publication Type: Case Reports, Journal Article)
Topics
  • Aged
  • Biopsy, Fine-Needle
  • Carcinoma, Medullary (diagnosis, pathology)
  • Diagnosis, Differential
  • Diagnostic Errors
  • Humans
  • Male
  • Thyroid Neoplasms (diagnosis, pathology)

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