An 18-year-old Caucasian man arrived at an urgent care center complaining of bilateral leg
pain and weakness. His
creatine kinase (CK) concentration was 13,220 IU/L. He was diagnosed with
rhabdomyolysis and instructed to go to the emergency room. He admitted to decreased urine output for four to five days before hospital admission. He had no significant past medical history, and his medications before symptom onset included
Hydroxycut four caplets by mouth daily,
naproxen sodium 220 mg by mouth as needed for
pain,
dextroamphetamine saccharate-
amphetamine salts (
Adderall) 15 mg by mouth once five days prior for a school examination, and
hydrocodone-
acetaminophen and
cyclobenzaprine for
pain. His social history revealed a recent increase in his exercise regimen, and his last alcoholic beverage was consumed five days prior. Upon admission, laboratory tests revealed elevated concentrations of CK, serum
creatinine (SCr),
aspartate transaminase,
alanine transaminase (ALT), and
alkaline phosphatase. The patient was diagnosed with
rhabdomyolysis and treated with intravenous hydration. The patient's leg tenderness was reduced, and he was discharged with instructions to stop
Hydroxycut, increase fluid intake, avoid alcohol consumption, and limit physical activity for the next week. Two weeks after hospital discharge, the patient's CK and liver
enzyme values returned to normal, excluding ALT and SCr, which remained slightly elevated, and his lower-extremity tenderness fully resolved.
CONCLUSION: An 18-year-old Caucasian man with no significant medical history developed
rhabdomyolysis possibly associated with the ingestion of
Hydroxycut in addition to his increased exercise regimen.