Abstract | BACKGROUND: Early glottic cancer can be cured with transoral laser resection, but in cases with anterior commissure involvement, there is still controversy concerning the best treatment modality. METHODS: The impact of anterior commissure involvement on local control was analyzed in a retrospective review of 444 patients with early glottic cancer (pT1a-pT2a) treated between 1986 and 2004 with transoral laser microsurgical resection. RESULTS: The anterior commissure was involved in 153 cases; the 5-year local control rate with and without anterior commissure involvement was 73% versus 89% for T1a and 68% versus 86% for T1b tumors. For T2a lesions, the 5-year local control rate was 76%, irrespective of anterior commissure involvement. CONCLUSION: In early glottic cancer treated by transoral laser microsurgery, a decrease in local control is evident in case of anterior commissure involvement for T1a and T1b but not for T2a tumors.
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Authors | Ralph M W Rödel, Wolfgang Steiner, Roland M Müller, Martina Kron, Christoph Matthias |
Journal | Head & neck
(Head Neck)
Vol. 31
Issue 5
Pg. 583-92
(May 2009)
ISSN: 1097-0347 [Electronic] United States |
PMID | 19132720
(Publication Type: Journal Article)
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Topics |
- Adult
- Aged
- Aged, 80 and over
- Carcinoma
(mortality, pathology, surgery)
- Female
- Glottis
(surgery)
- Humans
- Laryngeal Neoplasms
(mortality, pathology, surgery)
- Laryngoscopy
- Laser Therapy
- Lasers, Gas
- Male
- Microsurgery
- Middle Aged
- Neck Dissection
- Neoplasm Recurrence, Local
- Neoplasm, Residual
(surgery)
- Postoperative Complications
- Retrospective Studies
- Salvage Therapy
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